Cardiac Recovery After Recent Myocardial Infarction: Feasibility and Safety Intracoronary Injection of CD133-Positive Enriched Bone Marrow Progenitor Cells
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چکیده
Jozef Bartunek, Marc Vanderheyden, Bart Vandekerckhove, Samer Mansour, Bernard De Promotes Cardiac Recovery After Recent Myocardial Infarction: Feasibility and Safety Intracoronary Injection of CD133-Positive Enriched Bone Marrow Progenitor Cells Print ISSN: 0009-7322. Online ISSN: 1524-4539 Copyright © 2005 American Heart Association, Inc. All rights reserved. is published by the American Heart Association, 7272 Greenville Avenue, Dallas, TX 75231 Circulation doi: 10.1161/CIRCULATIONAHA.104.522292 2005;112:I-178-I-183 Circulation. http://circ.ahajournals.org/content/112/9_suppl/I-178 World Wide Web at: The online version of this article, along with updated information and services, is located on the
منابع مشابه
Intracoronary injection of CD133-positive enriched bone marrow progenitor cells promotes cardiac recovery after recent myocardial infarction: feasibility and safety.
BACKGROUND Bone marrow CD133-positive (CD133+) cells possess high hematopoietic and angiogenic capacity. We tested the feasibility, safety, and functional effects of the use of enriched CD133+ progenitor cells after intracoronary administration in patients with recent myocardial infarction. METHODS AND RESULTS Among 35 patients with acute myocardial infarction treated with stenting, 19 underw...
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Vanderheyden M, Kim HS, Kang HJ, Strauer BE, Vetrovec GW. Impact of intracoronary cell therapy on left ventricular function in the setting of acute myocardial infarction: a collaborative systematic review and meta-analysis of controlled clinical trials. J Am Coll Cardiol 2007;50:1761–1767. 18. Martin-Rendon E, Brunskill SJ, Hyde CJ, Stanworth SJ, Mathur A, Watt SM. Autologous bone marrow stem c...
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OBJECTIVES The long-term effect of intracoronary infusion of progenitor cells in patients with chronic ischemic cardiomyopathy. BACKGROUND Bone marrow stem-cell administration in patients with myocardial infarction improved myocardial performance and in some studies contributed to favorable left ventricular remodeling. METHODS We report on the results of a pilot, single center, controlled s...
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Bone marrow stem cell therapy has emerged as a promising approach to improve healing of the infarcted myocardium. Despite initial excitement, recent clinical trials using non-homogenous stem cells preparations showed variable and mixed results. Selected CD133(+) hematopoietic stem cells are candidate cells with high potential. Herein, we report the one-year safety analysis on the initial 20 pat...
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Autologous bone marrow cell transplantation (BMCs-Tx) is a promising novel option for treatment of cardiovascular disease. We analysed in a randomized controlled study the influence of the intracoronary autologous freshly isolated BMCs-Tx on the mobilization of bone marrow-derived circulating progenitor cells (BM-CPCs) in patients with acute myocardial infarction (AMI). Sixty-two patients with ...
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